Now I have gained a bit more experience with Prezi. Actually, I like the idea. Following Wikipedia, it is not a new one. In 2007, some artist suggested this style.
There are serious disadvantages. For one, Prezi is commercial. The full version takes 159$ per year. This allows to use the software offline, called Prezi Desktop. There are academic plans billing 59$ yearly. That sounds okay. But commercial means not open too. So you will not be able to apply external tools to your work. You are also working with a closed file format, which may or may not become obsolete some day.